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The SysMO Projects


Eleven out of 32 collaborative projects have been selected for funding within SysMO. Working groups from the six partner countries Austria (2), Germany (29), Norway (7), Spain (9), The Netherlands (15) and the United Kingdom (22) as well as from the Czech Republic (1), France (2) and Switzerland (4) contribute their experience and knowledge and will ensure the success of the SysMO initiative. The projects are covering different fields of interests and will be supported by the partner institutions with appr. 28 M €.


Project 1: BaCell-SysMO

The transition from growing to non-growing Bacillus subtilis cells - A systems biology approach


Project 2: COSMIC

Systems Biology of Clostridium acetobutylicum - a possible answer to dwindling crude oil reserves


Project 3: SUMO

Systems Understanding of Microbial Oxygen Responses


Project 4:

Ion and solute homeostasis in enteric bacteria: an integrated view generated from the interface of modelling and biological experimentation


Project 5:

Comparative Systems Biology: Lactic Acid Bacteria


Project 6: PSYSMO

Systems analysis of biotech induced stresses: towards a quantum increase in process performance in the cell factory Pseudomonas putida


Project 7:

Systems Biology of a genetically engineered Pseudomonas fluorescens with inducible exo-polysaccharide production: analysis of the dynamics and robustness of metabolic networks


Project 8: MOSES

MicroOrganism Systems Biology: Energy and Saccharomyces cerevisiae


Project 9: TRANSLUCENT

Gene interaction networks and models of cation homeostasis in Saccharomyces cerevisiae


Project 10: 

Global metabolic switching in Streptomyces coelicolor


Project 11:

Silicon cell model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation